In "Lonesome Dove," the protagonist expresses a disillusionment with men, indicating a deep-seated mistrust that stems from past experiences. This sentiment suggests that she has faced disappointments that have led her to conclude that she cannot rely on the intentions of most men. Her resolve to not expect anything from them showcases her desire to protect herself from further emotional pain.

This perspective reflects a broader theme of self-reliance and emotional resilience, highlighting how past experiences shape one's views on relationships. By deciding to distrust the "general run of men," the character takes a stand against vulnerability, choosing to navigate her life independently rather than risk disappointment again.