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Damasio has produced an influential theory about emotion-laden decision making, rooted in the philosophies of Hume and William James; this will soon be discussed.61 Briefly, the frontal cortex runs "as if" experiments of gut feelings-"How would I feel if this outcome occurred?"-and makes choices with the answer in mind. Damaging the vmPFC, thus removing limbic input to the PFC, eliminates gut feelings, making decisions harder."

( Robert M. Sapolsky )
[ Behave: The Biology of Humans ]
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