Moreover, sustained stress and glucocorticoid exposure enhance LTP and suppress LTD in the amygdala, boosting fear conditioning, and suppress LTP in the frontal cortex. Combining these effects-more excitable synapses in the amygdala, fewer ones in the frontal cortex-helps explain stress-induced impulsivity and poor emotional regulation.
( Robert M. Sapolsky )
[ Behave: The Biology of Humans ]
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