In 1904, significant changes occurred within the American food and drug regulations, specifically regarding Coca-Cola. During this time, the beverage company removed cocaine from its formula, marking a pivotal moment in the country's history. This shift led to a generation of Americans who were heavily influenced by alcohol and faced various health hazards, potentially fostering the resilience and mindset needed for the challenges of World War II.

Thomas Pynchon's novel "Gravity's Rainbow" reflects on this historical context, suggesting that the removal of cocaine from Coca-Cola contributed to shaping a society that became adept at handling the turmoil of war. By highlighting this event, Pynchon illustrates the broader implications of dietary and pharmaceutical changes on American culture and behavior during a critical period in history.