The quote from Voltaire emphasizes a crucial aspect of wisdom: the realization that most people are primarily focused on their own lives and struggles, often oblivious to the concerns of others. This understanding reflects a deeper awareness of human nature and the often self-centered perspective that individuals maintain. In this context, it connects to the themes in "The Confessions of Nat Turner," where the characters grapple with their personal dilemmas against a backdrop of societal turmoil.

In the book by William Styron, the narrator reflects on his ignorance regarding the lives of others, specifically his lack of knowledge about another person and their relationship. This highlights the isolation and inward focus that can exist among individuals, despite the complexity of the world around them. Styron's work invites readers to ponder the significance of empathy and the importance of understanding others while recognizing that everyone is fighting their own battles.