The quote underscores the theme of the complexity of human emotions and the difficulties in understanding one another. The character attempts to gauge the woman's feelings through a simple gesture, her handclasp, but finds himself unable to grasp the true depth of her feelings. This reveals a sense of helplessness and the limitations of human connection.

In "All the Pretty Horses," Cormac McCarthy explores the challenges of communication and intimacy. The character's inability to read the woman's heart reflects a broader commentary on the intricacies of relationships, where external signals often do not reveal inner truths. This moment captures the essence of longing for connection yet facing the barriers that exist between individuals.