The character in "Rabbit Redux" experiences a profound sense of inner turmoil, describing a feeling of sickness that arises from the weight of the world's troubles. The imagery of a crater suggests an emptiness or void that has formed within him, representing the inefficacy of external remedies like syrups and pills to alleviate his emotional and psychological pain. This reflects a deeper disillusionment and the struggle against overwhelming despair.

John Updike illustrates how superficial solutions fail to address the profound issues affecting the individual. The character's suffering transcends physical discomfort and delves into existential dread, indicating a connection between personal pain and the broader suffering present in society. This highlights the theme of searching for meaning and solace in a chaotic world, while also revealing the limits of materialistic approaches to dealing with deep-seated emotional struggles.