In the quote by Michael Crichton from "The Lost World," he emphasizes the importance of understanding history and psychology in the design process. He argues that merely relying on mathematical principles is insufficient when creating for human beings, as their behaviors and emotions can disrupt even the most precise calculations. This underscores the human element in design, highlighting that it is critical to consider the context in which people exist.

Crichton suggests that a designer's failure to incorporate knowledge of human history and psychology can lead to ineffective designs. If people do not respond as intended to a design, it reflects not just their unpredictability, but also the shortcomings of the designer's approach. Therefore, a comprehensive understanding of human nature is essential for effective design that resonates with users.