The quote reflects a deep emotional struggle of the character Desmond, suggesting that he grapples with intense feelings of fear and sadness. The imagery of him trying to "shrink inside his clothes" conveys a desire to hide or retreat from the world, indicating a profound inner turmoil. This illustrates not only his personal struggles but also hints at the broader themes of vulnerability and human fragility that are often explored in literature.

In "The New Iberia Blues," James Lee Burke delves into the complexities of human emotions through characters like Desmond. The narrative captures the essence of the characters' internal battles, allowing readers to empathize with their experiences. Such poignant insights into character development enrich the story, inviting readers to reflect on the nature of sorrow and fear that many individuals face, making the narrative both relatable and powerful.