The quote "Knowledge is often a responsibility nobody wants" from Cecelia Ahern's book "Flawed" suggests that possessing knowledge can be burdensome. It implies that understanding complex truths or realities often brings with it a sense of obligation that can be overwhelming or unwelcome. Many people might prefer ignorance to avoid the weight of this responsibility, highlighting a common tension between awareness and the desire for simplicity in life.

Ahern's narrative explores themes of morality and the challenges that arise when individuals are faced with difficult decisions influenced by their understanding of right and wrong. The quote encapsulates a profound struggle: while knowledge can empower individuals, it can also lead to feelings of isolation and despair when they feel they must confront harsh realities alone.