The quote reflects the idea that often we do not fully appreciate the worth of something until it is nearly taken from us. This notion resonates with many experiences in life, where the fear of loss can lead us to recognize the significance of what we have. The sentiment suggests a common human tendency to take things for granted until faced with the possibility of losing them.

In "The Tenth Circle" by Jodi Picoult, this theme of valuing relationships and experiences after confronting challenges or potential loss is explored. It emphasizes personal growth and understanding, portraying how moments of crisis can bring clarity and deepen our appreciation for what we hold dear.