In Cormac McCarthy's "All the Pretty Horses," the quote reflects a poignant piece of wisdom shared by the narrator's father. It suggests that one should avoid fixating on problems or grievances that affect their well-being. This advice emphasizes the importance of recognizing the negative impact of internal struggles and the necessity to let go of things that cause distress.

The message of the quote resonates throughout the novel, underscoring themes of resilience and self-awareness. Characters must navigate their challenges while learning to confront their fears and regrets, ultimately highlighting the journey toward personal growth and understanding.