In "Against the Day," Thomas Pynchon explores a range of themes through a complex narrative. The phrase "Now single up all lines!" suggests a call to streamline or focus efforts, reflecting the interconnectedness of various characters and their journeys. The book weaves together elements of history, technology, and capitalism while offering a critical lens on societal structures.

The narrative is rich with symbolism and Pynchon's signature style, blending the fantastical with the philosophical. This command can be interpreted as an invitation to examine and align the many threads of existence, highlighting the necessity of clarity in a chaotic world. It emphasizes the importance of understanding one's direction amid the tumult of life's experiences.