In Herman Melville's "Moby-Dick," the quote highlights the complexities of human nature and the potential for disorder within mankind. It suggests that, among various tools and instruments employed, human beings often exhibit the greatest tendency to become disordered or dysfunctional. This reflects on the unpredictable aspects of human behavior, especially when faced with the vastness and mystery of the natural world, represented by the moon's shadow.

The idea emphasizes that while tools can malfunction, human beings possess their own unique challenges. Their emotions, thoughts, and actions can become chaotic, leading to turmoil. This acknowledgment of the inherent flaws in humanity adds depth to the narrative, inviting readers to contemplate the relationship between humans and their environment, as well as the broader existential dilemmas depicted throughout the novel.