The quote "Seeing her sitting there unresponsive makes me realize that silence has a sound" from Jodi Picoult's "My Sister's Keeper" emphasizes the profound impact of silence in moments of emotional turmoil. It suggests that when someone is emotionally or physically absent, their silence speaks volumes, conveying deep feelings of loss, despair, or confusion. This observation underscores the weight of unexpressed words and highlights how silence can be just as powerful as speech.

This sentiment resonates in the context of family struggles, particularly when dealing with serious illness or grief. It illustrates the struggle that characters face as they navigate their relationships and the unspoken truths that often linger in such situations. The quote serves as a poignant reminder that even in quiet moments, there are rich, unarticulated emotions that can be heard loud and clear, shaping the experiences of those involved.