In her novel "Handle with Care," Jodi Picoult explores the complexities of life and how dreams often take a backseat to reality. The saying "That's what happens to dreams, life gets in the way" reflects the challenges individuals face when trying to achieve their aspirations amidst everyday obstacles. This theme resonates throughout the narrative as characters grapple with their desires and the unforeseen circumstances that impede their progress.

The book illustrates how personal struggles, relationships, and societal expectations can overshadow dreams. Through compelling storytelling, Picoult invites readers to reflect on their own experiences with ambition and the impact of life's unpredictability on their goals. The characters' journeys reveal that while dreams may falter, the resilience to navigate life's challenges remains paramount.