In "Rabbit Is Rich," John Updike explores the complex relationship between humanity and disaster. The character Harry recognizes that calamities often resonate deeply with people's inner feelings of guilt. These moments compel individuals to reflect on their lives and seek solace in spirituality, indicating a longing for connection with something greater than themselves.

This theme highlights the paradoxical nature of disaster, as it simultaneously brings suffering and a chance for redemption. Updike suggests that in the face of turmoil, there is a unique opportunity for self-examination and a return to faith, showcasing the intricate bond between life’s challenges and spiritual introspection.