The quote from John Steinbeck's "East of Eden" highlights the distinction between greatness and mediocrity. It suggests that mediocrity is a common condition faced by many individuals, making it easier for them to accept their status. In contrast, those who achieve greatness often experience isolation as a consequence of their exceptional abilities or qualities. This loneliness might stem from the lack of peers who can relate to their level of achievement.

Moreover, Steinbeck's reflection implies that while mediocrity might offer comfort in numbers, greatness demands a unique resilience. The loneliness associated with being great can be seen as a burden, but it also signifies the extraordinary nature of such individuals. By contrasting these states, Steinbeck encourages readers to contemplate the emotional weight that accompanies both mediocrity and greatness.