This quote encapsulates the essence of innovation and the entrepreneurial spirit that drives many successful venture capitalists and startup founders. Taking technical risks is often what separates groundbreaking technologies and companies from the rest. It requires courage and foresight to invest in or pursue advancements that are unproven or carry significant uncertainty. By embracing these risks, Khosla Ventures demonstrates a commitment to pushing the boundaries of what's possible, contributing to technological progress that can transform industries and improve lives.

In the landscape of innovation, many successful ventures have faced skepticism and doubt because their ideas challenge existing paradigms. The willingness to explore uncharted territory can lead to revolutionary solutions, but it also involves a higher likelihood of failure. The key is having a vision that recognizes the potential upside of risk-taking and the understanding that failure is often a part of the journey towards success.

This approach also reflects a principles-driven mindset—prioritizing breakthroughs over mere incremental improvements. It highlights the importance of having conviction in visionary ideas and being prepared to support them even when others hesitate. Investors and entrepreneurs who adopt this philosophy may tip the scales in favor of discovery and invention, creating technologies that might have seemed too daring or uncertain to others.

Ultimately, this quote encourages an attitude of boldness and resilience, emphasizing that progress often depends on those willing to venture into the unknown. It invites the broader community of investors, startups, and innovators to embrace calculated risks, knowing that such efforts can lead to extraordinary accomplishments and redefine the future.