In this quote from Carl Hiaasen's book Nature Girl, the speaker humorously expresses a sense of frustration with humanity, implying that they are attempting to address or correct the collective flaws of people, often focusing on individuals they find particularly difficult or problematic. The phrase "fix the entire human race" suggests an ambitious, perhaps impossible, goal of moral or societal improvement.

"One flaming asshole at a time" adds a sarcastic tone, highlighting the speaker's disdain for certain individuals or behaviors. This witty remark underscores the challenge and sometimes futile effort involved in trying to improve or change human nature, emphasizing the writer's sardonic view of human imperfections.