The quote from Jeffrey Eugenides' book "Middlesex" emphasizes that the significance of life is deeply intertwined with the concept of death. It suggests that the awareness of mortality shapes our experiences and gives meaning to our existence. By acknowledging the inevitability of death, individuals may find a deeper appreciation for life and its fleeting moments.

This perspective can lead to a more profound understanding of what is truly important, helping people prioritize relationships, passions, and experiences over trivial concerns. In recognizing that life is temporary, one may seek to live more fully and authentically, embracing the richness of moments that would otherwise be taken for granted.