In the book "My Sister's Keeper" by Jodi Picoult, the narrative revolves around the complexities of familial bonds, especially in the face of illness and ethical dilemmas. The characters grapple with difficult choices relating to love, sacrifice, and autonomy, highlighting the emotional toll that such situations can have on relationships.

The quote, "You can stay up all night and still not count all the ways to lose the people you love," reflects the profound sorrow and anxiety that accompany the possibility of losing loved ones. It encapsulates the struggles faced by the characters as they navigate heart-wrenching decisions and the unpredictable nature of life and love.