The quote from Cormac McCarthy's "No Country for Old Men" emphasizes the importance of distinguishing between what can be controlled and what cannot. It encourages individuals to address issues they have the power to change while accepting those that are beyond their influence. This perspective not only alleviates unnecessary stress but also promotes a pragmatic approach to life's challenges.

By recognizing that some situations are merely aggravations without real significance, one can foster resilience and maintain peace of mind. This mindset allows for a more focused energy on solutions rather than dwelling on problems that cannot be resolved, ultimately leading to a more fulfilling life.