"The Absolutely True Diary of a Part-Time Indian" follows the life of Arnold Spirit Jr., a 14-year-old Native American boy living on the Spokane Indian Reservation. He is an aspiring cartoonist and faces numerous challenges due to his background. Despite his tough life, he is determined to escape the limitations imposed by his environment and seek a better future. Arnold's journey begins when he decides to leave the reservation school for a predominantly white high school, a move that leads to both opportunities and struggles.
At his new school, Arnold deals with the complexities of identity and the reactions of others, including his own community and classmates. His choice to attend this school results in feelings of alienation and creates tension with his friends and family. Yet, he also finds friendship and support in unexpected places, which helps him navigate the conflicts he faces while trying to bridge two different worlds.
The novel explores themes such as racism, poverty, and the search for belonging, all while using humor and vivid illustrations that reflect Arnold's thoughts and experiences. Through his stories, readers gain insight into the challenges Native American youth face, while also celebrating resilience and the power of dreams. Arnold's character embodies hope and determination, portraying a heartfelt journey towards self-acceptance and a brighter future.