The quote "You can't miss what you never had," from Hunter S. Thompson's book "Polo Is My Life," suggests that absence does not lead to longing for something one has never experienced. It implies that if someone has not encountered something in their life, they are unlikely to feel a sense of loss or desire for it. This perspective encourages readers to reflect on their own experiences and the things they may yearn for despite never having had them.

This idea can also highlight the importance of context in understanding personal fulfillment and happiness. If we focus only on what we have known, it can shape our desires and priorities. Yet, contemplating the unknown can open up new possibilities and paths. Overall, Thompson's quote invites contemplation on what influences our feelings of want and loss, leading to a deeper understanding of our personal journeys.