In "Queen Isabella: Treachery, Adultery, and Murder in Medieval England," Alison Weir explores the tumultuous life of Queen Isabella, highlighting her political maneuverings and complex relationships. The narrative delves into themes of betrayal and passion, depicting how Isabella's actions shaped the political landscape of medieval England. The historical context is enriched by references to primary sources like the works of Robert of Reading and Murimuth, offering a well-rounded perspective on her life.

Weir's account draws from various historical documents, including the Monasticon by Dugdale, which provides insights into the period's religious and social structures. Through a blend of narrative and analysis, the book paints a vivid picture of Isabella as both a powerful queen and a woman caught in a web of personal and political conflict, ultimately leading to her involvement in significant historical events such as the fall of her husband, King Edward II.