In "Of Mice and Men," John Steinbeck explores the profound need for companionship through the character's reflections on loneliness. The quote emphasizes that every man requires someone close to him, highlighting how isolation can lead to despair and mental instability. The sentiment transcends individual identities; what matters is the human connection that sustains emotional well-being.

The narrative illustrates that when a person feels alone, they can lose their sense of purpose and health. Steinbeck's work poignantly captures this universal struggle, showing how companionship is vital for a fulfilling life, as loneliness can drive one to madness or sickness. In this way, the message about the importance of relationships resonates throughout the story.