In George Eliot's "Middlemarch," the quote reflects the idea that a person's strong commitment to meaningful goals can empower them to endure minor challenges and opposition. The memory of influential figures who have also faced struggles serves as a source of inspiration and support. These historical figures become symbolic patrons, encouraging individuals to persevere through their own difficulties.

This notion emphasizes the importance of legacy and mentorship, even from those who have long passed. The struggles of these great workers remind us that overcoming adversity is a common human experience, and their accomplishments offer hope and guidance. Thus, the presence of these "patron saints" reinforces the idea that dedication to noble causes is a worthy pursuit, capable of providing strength in times of hardship.