In the opening of Thomas Pynchon's "Gravity's Rainbow," the phrase "A screaming comes across the sky" evokes an intense and foreboding atmosphere. This imagery suggests an impending disaster or significant event, hinting at a deep sense of urgency. The use of "screaming" emphasizes the unsettling nature of the experience, conveying both fear and attention. It acts as a precursor to the chaos that follows, drawing readers into a world marked by uncertainty.

The assertion that "it has happened before, but there is nothing to compare it to now" underscores the uniqueness of the current situation. This reflects a cyclical understanding of history and trauma, suggesting that while past events may have echoed with similar themes, the present holds an unprecedented weight. This line encapsulates the novel's exploration of themes such as fate, war, and the human condition, inviting readers to consider the implications of events that resonate deeply yet remain incomparable in their impact.