In "A Prayer for Owen Meany," John Irving explores the profound impact of friendship and faith through the lives of the characters Owen Meany and John Wheelwright. The quote reflects the idea that Owen, despite his physical limitations, has always been a source of inspiration and strength for those around him. The imagery of "lifting up" signifies not only a physical act but also the emotional and spiritual support that John provides to Owen throughout their lives.

The narrative emphasizes themes of destiny and belief, with Owen believing he is an instrument of God's will. This belief aligns with the notion that he has been prepared for a greater purpose, underscoring how his unique characteristics shape their shared journey. The story ultimately examines how one's life can be intertwined with faith and friendship, leading to profound transformations and revelations.