In "Ender's Shadow," Orson Scott Card explores the timeless aspects of human behavior, emphasizing that the fundamental traits of humanity remain constant over time. The narrative delves into the psychological and social dynamics of individuals, particularly focusing on how character and instincts shape choices and actions. This unchanging nature of humans influences relationships, conflicts, and growth throughout the story.

The quote "Because human nature never changes" encapsulates the essence of the book, suggesting that regardless of advancements or circumstances, core human emotions and motivations persist. This theme serves as a backdrop for the characters’ development, illustrating how their responses to challenges are rooted in these enduring human qualities.