In Herman Melville's "Moby Dick," the quote highlights the inherent suffering of human existence. It suggests that life is filled with struggles and challenges, reflective of the tumultuous way in which we are brought into the world. The notion that pain is a fundamental aspect of life points to the idea that suffering is perhaps unavoidable and woven into the human experience.

By acknowledging that man is born in pain and must eventually die in anguish, the quote prepares readers for the harsh realities of life and mortality. It encapsulates Melville's exploration of existential themes, emphasizing the inevitability and significance of these experiences. This perspective compels readers to contemplate the complexities of life, suffering, and the acceptance of our fates.