In "State of Fear," Michael Crichton explores the intersection of science, politics, and advocacy. He argues that when truth-seeking becomes intertwined with political motivations, the integrity of knowledge diminishes. This conflation leads to a scenario where the primary aim shifts from understanding the facts to gaining influence or control. Crichton warns that this trend threatens the advancement of science and societal well-being.

Alston Chase's quote encapsulates this concern by highlighting the danger of prioritizing power over genuine inquiry. When knowledge is pursued solely as a means to an ideological end, it undermines its objective foundation. The quest for truth should remain independent of political agendas to ensure that it serves humanity rather than specific interests.