In "The Man in the High Castle," Philip K. Dick explores the impact of change on individuals within an alternate reality where the Axis powers won World War II. The narrative highlights the struggles faced by those who cannot adapt, illustrating how their lives are adversely affected. The harshness of change is a recurring theme, emphasizing that it often favors the strong while leaving the weaker individuals behind.

The quote, "But change's always harsh on the loser. Nothing new," encapsulates this sentiment. It points out the historical pattern of change benefiting the powerful and punishing those who cannot keep up. This reflects a broader commentary on society's relentless progress and the consequences it brings, particularly for those who find themselves on the losing end. Dick's work provokes thought about the nature of power, adaptability, and the often-unforgiving reality of life.