In "Darkness Visible: A Memoir of Madness," William Styron delves deep into the turmoil of depression, comparing its severity to that of chronic medical conditions like diabetes or cancer. He illustrates how depression is often underestimated, yet it can be equally debilitating, impacting the individual's life and well-being profoundly. Styron's reflections shed light on the pervasive nature of mental illness, emphasizing the need for understanding and recognition.

The memoir not only recounts Styron's personal battle with this overwhelming affliction but also serves as a poignant reminder of its seriousness. By sharing his experiences, he aims to destigmatize depression and encourage open discussions surrounding mental health, advocating for compassion and support for those suffering from such invisible struggles.