In George Eliot's "Middlemarch," the quote reflects the idea that beneath the facades people present to the world, there lies their true, vulnerable selves. The reference to a "big mask" suggests that individuals often hide their real emotions and insecurities behind an outward display meant to impress or convey strength. This concept emphasizes the depth of human experience, where anxiety and doubt linger beneath the surface, even in those who seem confident or powerful.

The image of "poor little eyes" and "timorous lips" evokes a sense of fragility and fear, highlighting the contrast between appearance and reality. It shows the struggle people face in balancing their public personas with their internal uncertainties. Eliot adeptly captures this tension, inviting readers to consider what lies beneath the surface of social interactions and the ways individuals manage their vulnerabilities amid societal expectations.