This quote from Charles Bukowski's Sifting Through the Madness for the Word, the Line, the Way encapsulates a stark, almost nihilistic perspective on life's trajectory. It suggests an unavoidable, relentless progression from start to finish marred by a refrain of resignation - "too bad, too bad, too bad." The repetition amplifies a sense of futility or lament, highlighting that throughout every phase of existence—from genesis through the midpoint and to the ultimate end—there remains an undercurrent of disappointment or sorrow.

Bukowski, known for his raw and unapologetic reflections on life's hardships, here distills a universal truth that life often presents challenges and regrets that cannot be escaped. The phrase "too bad" echoes like a mournful mantra, underscoring the inevitability of suffering or missed opportunities. Yet, it’s not just despair; it is also an acceptance of reality's harshness. This measured, repetitive acknowledgment could be interpreted as a call to confront life head-on without illusions, embracing its inherent imperfections.

In a broader sense, this quote invites us to reflect on how we perceive our journeys—whether we dwell on the negative or seek meaning despite adversity. It raises questions about the human tendency to dwell on loss or misfortune and challenges the reader to consider if resignation is the only response or if there is room for resilience and hope amid the "too bads." Bukowski’s stark outlook, while somber, can be a catalyst for deeper contemplation on acceptance and the nature of experience.