In Anne Rice's "The Witching Hour," the quote highlights the depth of knowledge and experience gained through extensive reading. A person who has immersed themselves in a thousand books brings rich insights and diverse perspectives, making them an engaging companion. Their familiarity with various ideas and narratives allows for meaningful conversations and connections, enriching their interactions with others.

Conversely, a person who has only read a few books might lack the breadth of understanding that fosters empathy and critical thinking. This limited knowledge can make them unpredictable and potentially dangerous, suggesting that ignorance can lead to misguided actions and harmful beliefs. The contrast emphasizes the profound impact that literature can have on character and interpersonal dynamics.