The character in "The Surgeon's Mate" by Patrick O'Brian reflects on the varied effects of wine on different individuals. He notes that while some people become irritable, argumentative, or overly emotional after drinking, he personally experiences no adverse changes. Instead, he finds that wine enhances his feelings of goodwill towards others and contributes to a more positive view of the world around him.

This observation highlights the subjective nature of alcohol's impact, revealing how it can influence behavior in contrasting ways. While for some, it leads to negativity, for him, it serves as a social lubricant that increases his appreciation for life's cheerfulness. His contemplation underscores the complexity of human reactions to substances and the broad spectrum of experiences they can create.