In "Gulp: Adventures on the Alimentary Canal," Mary Roach explores the medical circumstances surrounding Elvis Presley's death through the perspective of his physician, Nichopoulos. On the night Presley died, he was notably heavier than usual, a condition that peaked at different times due to his fluctuating weight. This variation could be as dramatic as a twenty-pound difference from one performance to the next, revealing the impact of his diet and health on his physical appearance.

Roach describes how Presley was attempting to alleviate his discomfort that night by trying to empty his bowels, which he struggled with. Nichopoulos indicates that Presley was holding his breath and exerting effort, much like someone suffering from constipation. This detail highlights the significant health issues Elvis faced, illustrating a grim intersection of celebrity lifestyle and personal health challenges at the time of his death.