In "Heart of Darkness," Joseph Conrad explores themes of isolation and existential despair through the protagonist's reflections. The quote illustrates a profound sense of loneliness that stems from a loss of belief and purpose, suggesting that the absence of these fundamental aspects leads to an emptiness that is difficult to endure. This feeling resonates with the overarching journey in the novel, where the characters confront their inner darkness and the harsh realities of colonialism.

The sense of desolation expressed in the quote emphasizes the emotional and psychological turmoil faced by individuals when they feel disconnected from their fate or core beliefs. As the protagonist traverses the dense and enigmatic landscapes of the Congo, he grapples with the implications of his own existence and the moral void he encounters. This exploration of loneliness and the search for meaning makes "Heart of Darkness" a powerful commentary on the human condition and the impacts of imperialism.