The quote highlights the internal struggles of Mr. Casaubon in George Eliot's "Middlemarch." It suggests that self-doubt can be one of the most challenging aspects of our existence. Mr. Casaubon grapples with feelings of insecurity regarding his relationship, especially the fear that he is no longer loved without reservations. His suspicions about being adored only when devoid of flaws reveal a deeper introspection about the nature of love and acceptance.

Moreover, the irony lies in Casaubon's realization that his fear is not entirely unfounded; he acknowledges his own shortcomings but does not fully admit them. This creates a sense of isolation, as he desires the comfort of a partner who would overlook his imperfections. Eliot explores the complexity of human relationships, emphasizing how self-doubt can complicate the connections we have with others and the longing for unconditional understanding.