In "The First Phone Call from Heaven," Mitch Albom explores themes of life, death, and the mysteries of the afterlife. The narrative suggests that human worries often stem from uncertainty about the future. The characters grapple with their fears and anxieties, which are reflected in their experiences and the profound events occurring in their lives.

The quote, "If we knew what comes next, we never would have worried," highlights the concept that knowing the future could alleviate our concerns. This insight invites readers to reflect on the nature of worry and the unknown, suggesting that acceptance and faith in uncertain times can lead to a more peaceful existence.