The quote from Margaret Atwood's "The Blind Assassin" reflects on the concept of foreknowledge and its potential consequences on human existence. If a person were aware of all future events and the outcomes of their actions, it would strip away the spontaneity and joy that come with life. This certainty might render them inactive and devoid of basic human experiences, such as love, laughter, and desire. Thus, knowing everything could lead to a profound sense of isolation and despair, akin to a lifeless state.

Atwood emphasizes that not knowing the future is integral to our humanity. The uncertainty allows us to embrace experiences fully, take risks, and form meaningful connections with others. The quote poignantly illustrates that the unpredictability of life is what makes it worth living. Without the possibility of joy and the thrill of the unknown, existence would be bleak and unfulfilling, akin to being "a stone." This profound insight prompts readers to appreciate the beauty of living in the moment and accepting life's inherent uncertainties.