In Shakespeare's "Measure for Measure," the quote highlights the responsibility that comes with great power. The idea conveyed is that while possessing immense strength or authority can be impressive and beneficial, it becomes oppressive when misused. This duality of power emphasizes the moral implications of wielding such strength without regard for others.

The character Isabella's reflection serves as a poignant commentary on the ethical use of power. It suggests that true strength should be exercised with care and justice, rather than tyranny. Thus, the quote stresses the importance of using one’s capabilities wisely to avoid causing harm and to uphold fairness in society.