In Cormac McCarthy's "All the Pretty Horses," the quote reflects the theme of self-betrayal and the consequences of cowardice. It suggests that when a person fails to stand up for themselves, they become susceptible to further betrayals, both from themselves and others. This initial act of abandoning one’s own principles paves the way for a lack of integrity, making it easier to succumb to additional treachery.

The statement also highlights the internal struggle faced by individuals who might prioritize fear over their convictions. This cowardice leads to a cycle where personal failures trigger a domino effect of external betrayals, ultimately portraying the fragile nature of trust and loyalty in both oneself and in relationships with others.