The quote from Ken Kesey's "Sometimes a Great Notion" suggests that individuals will go to great lengths to avoid the pain of loneliness, even resorting to drastic actions against themselves. This reflects a deep human fear of isolation and the lengths to which people will go to maintain connections with others. The notion indicates that loneliness can drive individuals to make significant sacrifices to preserve their relationships or their sense of belonging.

This theme resonates widely, as many can relate to the discomfort of being alone. It highlights the fundamental human need for companionship and the lengths people will go to evade feelings of loneliness, emphasizing that such desperation can sometimes lead to self-destructive choices. Ultimately, Kesey's work prompts readers to reflect on the balance between individuality and the need for social connection.