The quote "My own preferences had little bearing on the outcome of events" from Curtis Sittenfeld's novel Sisterland reflects the theme of how personal desires often have limited influence on life's directions. The story explores the complexities of life choices and the unpredictable nature of fate, highlighting that individuals might find themselves at the mercy of circumstances beyond their control.

This realization can lead to introspection and a deeper understanding of one's role in the grand scheme of things. The protagonist learns that, despite their intentions or wishes, external factors and the choices of others can significantly shape their life experiences, bringing to light the intricate web of interconnected decisions and occurrences.