The quote emphasizes the futility of attempting to silence critics or slanderers. It suggests that no matter how much effort one puts into appeasing negative voices, there will always be someone ready to speak against you. Just as controlling the winds is impossible, so is stopping the flow of gossip and slander.
This insight reflects a broader truth about human nature and public perception. Instead of getting bogged down by external opinions, one should focus on their own path and values. Ultimately, it's more productive to pursue one's goals than to waste time worrying about the judgments of others.