In his reflection on knowledge and the limits of human understanding, John Steinbeck expresses a profound sense of uncertainty about the world. He contrasts his own lack of awareness about even basic happenings in life with the deep insights of his grandfather, who seemed to possess wisdom about the universe's mysteries. This disparity highlights the challenges of grasping life's complexities and the feeling of being adrift in an incomprehensible reality.

Steinbeck's contemplation underscores the futility of opinions when rooted in ignorance. He emphasizes that without a solid foundation of knowledge, it becomes difficult to form meaningful thoughts or beliefs. His acknowledgment of life's uncertainties evokes a sense of humility and invites readers to reflect on their own understanding of existence, ultimately suggesting that many questions remain unanswered and that certainty is elusive.